Microgravity-Induced Fluid Shift and Ophthalmic Changes
نویسندگان
چکیده
منابع مشابه
Microgravity-Induced Fluid Shift and Ophthalmic Changes
Although changes to visual acuity in spaceflight have been observed in some astronauts since the early days of the space program, the impact to the crew was considered minor. Since that time, missions to the International Space Station have extended the typical duration of time spent in microgravity from a few days or weeks to many months. This has been accompanied by the emergence of a variety...
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Prolonged microgravity exposure alters human skeletal muscle by markedly reducing size, function, and metabolic capacity. Preserving skeletal muscle health presents a major challenge to space exploration beyond low Earth orbit. Humans express three distinct pure myosin heavy chain (MHC) muscle fiber types (slow fast: MHC I, IIa, and IIx), along with hybrids (MHC I/IIa, IIa/IIx, and I/IIa/IIx). ...
متن کاملSimulated microgravity-induced aortic remodeling.
We have previously shown that microgravity and simulated microgravity induce an increase in human and rat aortic stiffness. We attempted to elucidate the mechanism(s) responsible for this increase in stiffness. We hypothesize that an alteration in vessel wall collagen or elastin content or in extracellular matrix (ECM) cross-linking either individually or in a combination is responsible for the...
متن کاملMicrogravity-induced changes in aortic stiffness and their role in orthostatic intolerance.
Microgravity (microG)-induced orthostatic intolerance (OI) in astronauts is characterized by a marked decrease in cardiac output (CO) in response to an orthostatic stress. Since CO is highly dependent on venous return, alterations in the resistance to venous return (RVR) may be important in contributing to OI. The RVR is directly dependent on arterial compliance (C(a)), where aortic compliance ...
متن کاملTitle: Microgravity Induced Changes in Aortic Stiffness and its Role in Orthostatic Intolerance
Microgravity (μG) induced orthostatic intolerance (OI) in astronauts is characterized by a marked decrease in cardiac output (CO) in response to an orthostatic stress. Since CO is highly dependent on venous return, alterations in the resistance to venous return (RVR) may be important in contributing to OI. The RVR is directly dependent on arterial compliance (Ca), where aortic compliance (Cao) ...
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ژورنال
عنوان ژورنال: Life
سال: 2014
ISSN: 2075-1729
DOI: 10.3390/life4040621